Grape Cookies Genetics
The Grape Cookies was created in 2016 by crossing male pollen from (Jäger X Grape Skunk Purple) on to a Cookies S1. The Cookies S1 was created by HENDRX and phenotype hunted by Wheeler and his family. The Cookies S1 became known as EyeScream Cake and delighted many on the legal and illicit markets of California. The Grookies Cut was gifted to HENDRX and Moca before either ever solidified themselves as DCC license holders. Avant garde and ahead of its time the Grookies was bred by Wheeler, and laid wait several years before emerging in public view.
Grape Cookies Cannabinoid Profile
Grown by Moca Humboldt and recognized by the California State Fair as a two-time gold medalist in 2022 and silver medalist in 2023, the Grookies has both bag appeal and a radical cannabinoid profile unlike anything on the market. Testing in the low to mid 20s THC percentage and 5-7 percent CBG. Ocimene dominant with equal parts limonene, linalool, and β-caryophyllene, the terps on this phenotype are unique and sugary. The greater implications of the Grape Cookies, however lies in the cannabinoid profile. Which, entirely unique, may carry medicinal and phytocannabinoid-terpenoid synergistic therapeutic significance. CBGa, which is the acidic pre-decarboxylated form of CBG, is the precursor phytocannabinoid to both THCa and CBDa. This means that CBG is converted into either CBD or THC naturally during the cannabis plant’s life. Biosynthesis genes in the cannabis plant determine the final outcome of CBGa, which commonly appears in very low relative concentrations. The Grookies however expresses a high level of CBGa and THCa conjunctively. This is unlike any other chemovar in the HENDRX library. This reflects that the Grape Cookies in both clone and seed is different than the vast majority of cannabis chemotypic profiles. In Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects, author Ethan Russo summarizes CBG potential applications as a muscle relaxant, analgesic and anti-erythmetic, anti fungal, a breast cancer treatment, prostate cancer treatment, antidepressant, and psoriasis solution (Russo 2011). Pre-clinical findings demonstrate that CBG reduces intraocular pressure, which is why Grape Cookies has been sought and utilized in conjunction with Ringo’s Gift Katie’s Cut and Levi’s Cut to treat macular degeneration (Calapai 2022 et al).
Grape Cookies Origin Story
Grape Cookies AKA The Grookies Seeds
References
Ethan Russo. “Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects”. British Journal of Pharmocology Volume 163, Issue 7, July 2011, Pages 1344-1364
Fabrizio Calapai, Luigi Cardia, Emanuela Esposito, Ilaria Ammendolia, Cristina Mondello, Roberto Lo Giudice, Sebastiano Gangemi, Gioacchino Calapai, Carmen Mannucci. “Pharmacological Aspects and Biological Effects of Cannabigerol and Its Synthetic Derivatives“, Evidence-Based Complementary and Alternative Medicine, Vol. 2022, Article ID 3336516, 14 pages
Prentout D, Razumova O, Rhoné B, Badouin H, Henri H, Feng C, Käfer J, Karlov G, Marais GAB. “An efficient RNA-seq-based segregation analysis identifies the sex chromosomes of Cannabis sativa.“ Genome Res. 2020 Feb;30(2):164-172. doi: 10.1101/gr.251207.119. Epub 2020 Feb 7. PMID: 32033943; PMCID: PMC7050526