The relationship between our plants and the systemic microbiology within cannabis is a mutualistic benefit for the environment, yield, and quality of the final product. Specifically, Pseudomonas & Bacillus which are naturally occurring in cannabis can colonize root tissue and become endophytes of the plant cells. Evidence supported by HENDRX research efforts demonstrate a significant increase in potency and yield of cannabis when early inoculation of plants with Sym3iotic+ microbial consortium takes place.